Dell PowerEdge R650 & R750 CPU Upgrade: Maximize Server Performance

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May 31
3 min read

Updated: Jun 4

If you're considering CPU upgrade options for your Dell PowerEdge R650 or R750 server, you're likely looking to boost performance for demanding workloads like virtualization, data processing, or enterprise applications.

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In this article, you'll find officially supported CPUs, upgrade considerations, and configuration tips.

Dell PowerEdge R650 and R750 CPU upgrade guide with supported Intel Xeon processors. Compare specs and boost server performance with the right processor.

Dell PowerEdge R650 Server: Supported CPUs

The PowerEdge R650 supports the 3rd Gen Intel® Xeon® Scalable family and features up to two sockets with 32 DDR4 DIMM slots.

✅ Verified CPU Models for Dell PowerEdge R650:

Processor	Cores/Threads	Base Clock	Cache	Max Memory Speed	TDP
Intel Xeon Platinum 8380	40 / 80	2.3 GHz	60 MB	3200 MT/s	270W
Intel Xeon Platinum 8368Q*	38 / 76	2.6 GHz	57 MB	3200 MT/s	270W
Intel Xeon Gold 6338	32 / 64	2.0 GHz	48 MB	3200 MT/s	205W
Intel Xeon Silver 4310	12 / 24	2.1 GHz	18 MB	2666 MT/s	120W

*8368Q requires liquid cooling due to higher thermal demands.

Memory Support:

Up to 10 TB total using RDIMM, LRDIMM, and Intel® Optane™ Persistent Memory 200 Series
Speeds vary by CPU: 3200 / 2933 / 2666 MT/s

Official Source: Dell PowerEdge R650 Technical Guide

PowerEdge R750: Supported CPU Options

The PowerEdge R750 also supports dual 3rd Gen Intel® Xeon® Scalable processors and up to 32 DIMMs per system, offering excellent flexibility for memory-heavy tasks.

✅ Verified CPU Models for R750:

Processor	Cores/Threads	Base Clock	Cache	Max Memory Speed	TDP
Intel Xeon Platinum 8352V	36 / 72	2.1 GHz	54 MB	2933 MT/s	195W
Intel Xeon Gold 6330	28 / 56	2.0 GHz	42 MB	2933 MT/s	205W
Intel Xeon Silver 4314	16 / 32	2.4 GHz	24 MB	2666 MT/s	135W

⚠️ Note: The Xeon Gold 6330N variant supports 3200 MT/s, but the 6330 listed here supports only 2933 MT/s.

Memory Support:

Up to 12 TB with Intel Optane + LRDIMM
Speed depends on CPU selection

Official Source: Dell PowerEdge R750 Technical Guide

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Dell PowerEdge R650 & R750 CPU Upgrade Considerations

Before upgrading, make sure to account for:

CPU Compatibility: Confirm the target processor is supported by your server model and BIOS.
Cooling: High-TDP CPUs like the 8368Q require enhanced thermal solutions.
Power: Ensure your PSU can handle the power requirements of upgraded CPUs.
Memory Pairing: Upgrade memory speeds only if the CPU supports higher frequencies.

Dell only supports CPU upgrades using original processors or kits (new or refurbished). Third-party CPUs are not validated and may void support coverage.

Dell PowerEdge R650 & R750 CPU UpgradeAdding a Second CPU

Planning to upgrade from a single to a dual-CPU configuration?

Both CPUs must be identical (same model, stepping, cache).
Populate memory evenly across both processors to maintain bandwidth and stability.
Update BIOS and firmware before installing.

Dell PowerEdge R650 & R750: Best Practices for CPU Upgrades

To ensure a successful upgrade:

✅ Buy only original Dell CPUs (new or refurbished) to retain warranty and compatibility assurance.
✅ Consult with your supplier for validation.
✅ Use ESD protection and follow Dell’s installation documentation.
✅ Test system stability and monitor thermals after installation.