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Supermicro SYS-421GE-TNHR2-LCC server with 8x NVIDIA H100 80GB SXM GPUs

  • Feb 28
  • 3 min read

Updated: Mar 1

This Supermicro SYS-421GE-TNHR2-LCC configuration delivers 8x NVIDIA H100 80GB SXM GPUs in a liquid-cooled 4U HGX platform, optimized for multi-GPU training and high-concurrency inference inside enterprise AI clusters.


Supermicro NVIDIA H100 Servers

Limited stock at special pricing



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Configuration overview: Supermicro SYS-421GE-TNHR2-LCC server with 8x NVIDIA H100 GPUs


The Supermicro SYS-421GE-TNHR2-LCC server is a 4U liquid-cooled platform built around an NVIDIA HGX H100 SXM 8-GPU baseboard. This type of system is typically deployed in enterprise AI clusters where power, cooling, GPU interconnect, and networking determine real performance.


It is commonly used for:

  • Multi-node training (distributed training with high-speed fabric)

  • Large-scale inference (high concurrency and batching)

  • Shared GPU infrastructure (virtualized or multi-tenant environments)

  • HPC + AI pipelines (depending on software stack)



Full configuration: Supermicro SYS-421GE-TNHR2-LCC server with 8x NVIDIA H100 GPUs


Base system: Supermicro SYS-421GE-TNHR2-LCC 4U liquid-cooled server

Component

Details

Why it matters

Server

Supermicro SYS-421GE-TNHR2-LCC

Integrated HGX platform (power, cooling, firmware alignment)

Form factor

4U, liquid-cooled (LCC)

Supports sustained GPU power in dense deployments

Condition

Brand new in crates

Clear baseline for acceptance testing

Commercial term

FOB (Free On-Board) Supermicro

Defines shipping handover point



GPUs: 8x NVIDIA H100 80GB SXM (HGX 8-GPU)

Component

Details

Why it matters

GPUs

8x NVIDIA H100 80GB SXM

High GPU memory capacity per node

GPU memory

80GB HBM2e per GPU

Helps fit larger models and higher batch sizes

Interconnect

NVLink + NVSwitch (HGX)

High GPU-to-GPU bandwidth for multi-GPU training

Practical note:

For multi-GPU training, NVSwitch topology is often the difference between “8 GPUs installed” and “8 GPUs scaling well.”



CPUs: 2x Intel Xeon Platinum 8558P

Component

Details

Why it matters

CPUs

2x Intel Xeon Platinum 8558P

Host CPU capacity and PCIe for GPUs, storage, and NICs

CPU generation

5th Gen Intel Xeon Scalable (Emerald Rapids)

Current platform generation for this class of server



Memory: 1TB DDR5 (16x 64GB)

Component

Details

Why it matters

Memory

1TB DDR5 (16x 64GB)

Headroom for preprocessing, dataloading, and multi-service nodes

Scalability note (platform capability):

The platform supports higher memory capacities depending on DIMM selection and speed targets. This matters for CPU-heavy pipelines and multi-tenant deployments.



Storage: 2x 960GB NVMe (OS) + chassis expandability

Component

Details

Why it matters

OS storage

2x 960GB NVMe

Fast boot, image pulls, and local cache

Front bays

8x hot-swap 2.5" NVMe U.2 bays (chassis support)

Optional local high-speed dataset / scratch

M.2

2x M.2 NVMe slots (platform support)

Common for mirrored boot or hypervisor OS

Configuration clarity:

This offer includes 2x 960GB NVMe installed. Remaining bays can be left empty or populated depending on project needs.



Networking: On-Board 10GbE + PCIe expansion for cluster fabric

Component

Details

Why it matters

On-Board LAN

2x 10GbE RJ45 (Intel X710-AT2)

Reliable management and baseline connectivity

Expansion

PCIe 5.0 slots available for fabric NICs

Enables InfiniBand or 100/200/400GbE for training



Power: High-capacity redundant PSUs (deployment-critical)

Component

Details

Why it matters

Power supplies

4x 5250W (2+2 redundant), Titanium efficiency

Required for 8x GPU power draw and stable operation



Cooling: liquid cooling requirements (what IT needs to know)


This is a liquid-cooled system designed for data center environments with appropriate infrastructure.


Typical LCC elements include:

  • Direct-to-chip (D2C) cold plates for major heat sources

  • Supporting fans for non-liquid-cooled components

  • Facility requirements for coolant loop integration and service procedures



Platform overview: Supermicro SYS-421GE-TNHR2-LCC server with 8x NVIDIA H100 GPUs


The Supermicro SYS-421GE-TNHR2-LCC server with 8x NVIDIA H100 SXM is built for teams that want:

  • Standard rack deployment and cluster scaling

  • Control of OS image, drivers, and monitoring

  • Predictable data handling and enterprise operations


Real performance depends on:

  • GPU topology (NVSwitch)

  • Cluster fabric (NIC choice + fabric tuning)

  • Software stack (driver versions, NCCL settings, container runtime, scheduler)


To keep this readable, those items should be validated during acceptance testing rather than described as guarantees.



Use cases: Supermicro SYS-421GE-TNHR2-LCC server with 8x NVIDIA H100 GPUs


Common deployments include:

  • LLM training with distributed frameworks and a high-speed fabric

  • Inference clusters with batching and concurrency tuning

  • Multi-tenant GPU hosting using MIG where appropriate

  • Enterprise AI platforms integrated with Kubernetes or Slurm



Testing, condition, and warranty: Supermicro SYS-421GE-TNHR2-LCC server with 8x NVIDIA H100 GPUs


Typical acceptance checks for an 8-GPU liquid-cooled server include:

  • GPU stability under sustained load

  • CPU + memory validation (ECC / mapping)

  • NVMe health and throughput

  • Firmware alignment (BIOS/BMC/GPU)

  • Thermal behavior at target power limits


This system is offered as:

  • Brand new in crates

  • FOB (Free On-Board) Supermicro

  • 3-year warranty


The Supermicro SYS-421GE-TNHR2-LCC with 8x NVIDIA H100 is designed for enterprise AI environments with proper data center power and cooling, a defined high-speed fabric for multi-node scaling, and a controlled, repeatable software lifecycle.


Supermicro NVIDIA H100 Servers

Limited stock at special pricing





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