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HPE ProLiant DL380 Server Comparison: Gen10 vs. Gen11 - Do You Actually Need an Upgrade?

  • Writer: Zo Jakab
    Zo Jakab
  • Aug 29, 2023
  • 3 min read

Updated: Aug 12

HPE ProLiant servers are among the most widely deployed enterprise rack servers in their class. The DL380 model is a versatile 2U system used across many industries.


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This comparison focuses on the differences between the HPE ProLiant DL380 Gen10 and the HPE ProLiant DL380 Gen11 — both Intel-based models.


HPE ProLiant DL380 Gen10 and Gen11 server comparison with Intel Xeon Scalable CPUs, DDR4 and DDR5 memory, PCIe 3.0 and PCIe 5.0 expansion, NVMe and EDSFF storage, HPE iLO management, enterprise data center, AI, cloud, and virtualization workloads. Compare. Refurbished. Server-parts.eu.


HPE ProLiant DL380 Gen10 vs Gen11: Specs Comparison


Specification

HPE ProLiant DL380 Gen10

HPE ProLiant DL380 Gen11

Processor Support

Up to 2× Intel® Xeon® Scalable (1st or 2nd Gen), max 28 cores per CPU

Up to 2× Intel® Xeon® Scalable (4th or 5th Gen “Sapphire Rapids” / “Emerald Rapids”), max 64 cores per CPU

Memory

24 DIMM slots (max 3.0 TB DDR4 with LRDIMM, 1.5 TB with RDIMM, up to 2933 MT/s)

32 DIMM slots (16 per CPU, max 8.0 TB DDR5, up to 5600 MT/s)

Storage

Up to 30× SFF or 19× LFF drives (varies by chassis), NVMe supported

Up to 20× EDSFF drives plus up to 8× additional SFF drives, NVMe supported

Expansion Slots

Up to 8× PCIe 3.0 slots

Up to 8× PCIe 5.0 slots

Networking

FlexibleLOM adapters supporting 1/10/25 GbE

OCP 3.0 adapters supporting 10/25/100 GbE

Power Supply

500 W, 800 W, or 1600 W Platinum/Titanium hot-plug

800 W, 1000 W, or 1600 W Platinum/Titanium hot-plug

Management

HPE iLO 5 with optional HPE OneView integration

HPE iLO 6 with HPE GreenLake for Compute Ops Management

Security

Silicon root of trust, TPM 2.0, Secure Boot

Enhanced silicon root of trust, TPM 2.0 (standard), SPDM support, platform certificates with iDevID

GPU Support

Up to 4× single-wide or 3× double-wide GPUs

Up to 8× single-wide or 3× double-wide GPUs

Form Factor

2U rack server

2U rack server

Cooling

Standard or high-performance fan kits

Advanced cooling for higher-power CPUs/GPUs

Operating Temp

10 °C to 35 °C

10 °C to 35 °C

Warranty

3-year parts, labor, and onsite

3-year parts, labor, and onsite

Note: Specifications may vary based on configuration and regional availability. For the most accurate and up-to-date information, please refer to HPE's official documentation or contact an authorized HPE representative.



HPE ProLiant DL380 Gen10: Key Features and Capabilities


  • Launch Year: 2017

  • CPU Platform: Intel Purley (Skylake-SP, Cascade Lake-SP)

  • Architecture & Design: Security-focused design with HPE’s silicon root of trust to protect firmware at boot.

  • Performance: Well-suited for virtualization, general compute, and storage-heavy workloads.

  • Management: HPE iLO 5 with optional OneView integration for on-premises infrastructure control.

  • Workloads: Best for traditional data center tasks, virtualization, and enterprise applications.

  • Ecosystem: Still widely supported, but limited to DDR4 memory and PCIe 3.0, which may restrict compatibility with some new components.



HPE ProLiant DL380 Gen11: Key Features and Capabilities


  • Launch Year: Late 2022

  • CPU Platform: Intel Sapphire Rapids / Emerald Rapids

  • Architecture & Design: Built for high core counts, faster memory, and higher I/O throughput.

  • Performance: Large improvements over Gen10 in per-core processing, memory bandwidth, and PCIe throughput.

  • Management: Ships with iLO 6 and HPE GreenLake for Compute Ops Management (SaaS-based, on-prem and hybrid support).

  • Security: Adds platform certificates, iDevID, and SPDM support for third-party component verification.

  • Workloads: Handles both traditional enterprise workloads and modern cloud-native or AI/ML deployments.

  • Ecosystem: Designed for DDR5, PCIe 5.0, and EDSFF storage, enabling adoption of the latest storage and accelerator technology.



Choosing Between HPE ProLiant DL380 Gen10 vs HPE ProLiant DL380 Gen11


When HPE ProLiant DL380 Gen10 is a good choice:

  • Existing infrastructure is Gen10-based, and you need to expand or replace servers without a platform change.

  • Budget constraints make refurbished Gen10 hardware attractive.

  • Workloads don’t require DDR5 memory, PCIe 5.0, or the highest core counts.


When HPE ProLiant DL380 Gen11 is a better fit:

  • You need maximum performance per rack unit.

  • You’re planning for AI/ML, large-scale virtualization, or high-performance storage systems.

  • You want modern management and security enhancements.



HPE ProLiant Servers: Save Up to 80%

✔️ No Upfront Payment Required - Test First, Pay Later!



Sources: HPE ProLiant DL380 Gen10 vs HPE ProLiant DL380 Gen11




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