HPE ProLiant DDR4 Memory Modules: Prices, Compatibility, Upgrade Options, RDIMM/LRDIMM Part Numbers
- Nov 14, 2025
- 4 min read
Upgrading or replacing DDR4 memory modules in HPE ProLiant servers is one of the most common tasks for anyone maintaining HPE Gen9, Gen10, or Gen10+ systems.
HPE ProLiant DDR4 Memory Modules: Save Up To 80%
✔️ 5-Year Warranty – No Risk: Pay Only After Testing
Whether you operate virtualization clusters, databases, storage nodes, or general workloads, choosing the right HPE ProLiant DDR4 memory module (RDIMM or LRDIMM) is essential for performance and stability.
What Is HPE ProLiant DDR4 Memory?
HPE ProLiant DDR4 memory, also known as HPE SmartMemory, is enterprise-grade ECC memory designed for HPE ProLiant servers. It provides:
ECC error correction
Lower failure rates
Full integration with iLO for diagnostics
Consistent performance under mixed workloads
Validation for specific ProLiant models
This type of memory is not the same as desktop DDR4 or laptop DDR4. Only ECC RDIMM and ECC LRDIMM modules are supported in HPE ProLiant servers.
HPE DDR4 RDIMM vs. LRDIMM for HPE ProLiant
HPE ProLiant Servers: DDR4 Memory
Both memory types are common in HPE ProLiant DDR4 environments, but they serve different needs.
RDIMM (Registered DIMM): DDR4 Memory
Best choice for general workloads
Lower latency
Supports 8GB–64GB per module
Most cost-effective
Common in HPE ProLiant DL380 and HPE ProLiant DL360 servers
LRDIMM (Load-Reduced DIMM): DDR4 Memory
Designed for higher capacity
Supports 64GB–128GB (and some 256GB) modules
Ideal for virtualization, HCI, SAP, databases
Slightly higher latency
Required if you want maximum memory per CPU
Critical Rule: DDR4 Memory
RDIMM and LRDIMM cannot be mixed in any HPE ProLiant server. The server will not boot if mixed.
HPE ProLiant DDR4 Memory Speeds and Server Generations
Different ProLiant generations support different DDR4 speeds:
Generation | Supported DDR4 Speeds | CPU Platform |
HPE ProLiant Gen9 | 2133 / 2400 MT/s | Intel Xeon E5 v3/v4 |
HPE ProLiant Gen10 | 2400 / 2666 MT/s | Intel Xeon Scalable Gen1 |
HPE ProLiant Gen10+ | 2933 / 3200 MT/s | Intel Xeon Scalable Gen2 |
Speed rules: DDR4 Memory
The final speed = the slowest module installed
More DIMMs per channel = lower effective speed
CPU model determines maximum possible speed
These rules apply to all HPE ProLiant DDR4 memory modules, regardless of density.
Most Popular HPE ProLiant DDR4 Memory Modules
16GB RDIMM – HPE ProLiant DDR4 Memory
726719-B21 – 16GB DDR4-2133 RDIMM
805349-B21 – 16GB DDR4-2400 RDIMM
815098-B21 – 16GB DDR4-2666 RDIMM (Gen10 SmartMemory)
32GB RDIMM – HPE ProLiant DDR4 Memory
728629-B21 – 32GB DDR4-2133 RDIMM
805351-B21 – 32GB DDR4-2400 RDIMM
P00924-B21 – 32GB DDR4-2933 RDIMM (Gen10/Gen10+ SmartMemory)
64GB LRDIMM – HPE ProLiant DDR4 Memory
726724-B21 – 64GB DDR4-2133 LRDIMM
805358-B21 – 64GB DDR4-2400 LRDIMM (very common Gen9/Gen10 part)
815101-B21 – 64GB DDR4-2666 LRDIMM (Gen10 SmartMemory)
128GB LRDIMM – HPE ProLiant DDR4 Memory
809208-B21 – 128GB DDR4-2400 LRDIMM
815102-B21 – 128GB DDR4-2666 LRDIMM (Gen10 SmartMemory)
These are the core HPE ProLiant DDR4 memory modules used in HPE ProLiant DL380, DL360, ML350, and storage servers.
Compatibility Rules for HPE ProLiant DDR4 Memory
These core rules prevent almost all memory-related issues in HPE ProLiant servers.
RDIMM and LRDIMM cannot be mixed: DDR4 Memory
Mixing them results in no POST.
Both CPUs must use the same DIMM layout: DDR4 Memory
Example:If CPU1 has 2 DIMMs per channel, CPU2 must also have 2 per channel.
Mixed speeds run at the slowest speed: DDR4 Memory
2666 + 2400 → everything runs at 2400.
Rank affects speed and capacity: DDR4 Memory
1Rx8 → rare, low capacity
2Rx8 → common 16GB
2Rx4 → common 32GB
4Rx4 → common 64GB/128GB LRDIMM
Maximum memory depends on your CPU: DDR4 Memory
Gen9 Xeon E5 → up to 768GB per server
Gen10 Xeon Scalable → up to 1.5TB per CPU
Gen10+ Scalable Gen2 → up to 2TB per CPU
DIMM population order matters: DDR4 Memory
Fill one DIMM per channel first, then the second.Wrong population reduces bandwidth or forces “unbalanced” mode.
Firmware must be up to date: DDR4 Memory
Old BIOS/iLO can cause:
“Unsupported DIMM” errors
Wrong speed detection
Failed POST after an upgrade
Mixed densities are allowed (RDIMM only): DDR4 Memory
You can mix 16GB and 32GB RDIMMs if channels stay balanced.Mixing densities in LRDIMM setups is not recommended.
High-capacity LRDIMMs need good airflow: DDR4 Memory
64GB/128GB LRDIMMs run hotter and may increase fan speeds
HPE ProLiant Servers Using DDR4 Memory
HPE ProLiant Gen9 Servers
HPE ProLiant DL380 Gen9
HPE ProLiant DL360 Gen9
HPE ProLiant ML350 Gen9
HPE ProLiant Gen10 Servers
HPE ProLiant DL380 Gen10
HPE ProLiant DL360 Gen10
HPE ProLiant ML350 Gen10
HPE Proliant Gen10+ Servers
HPE ProLiant DL360/380 Gen10+ with Xeon Scalable Gen2
Supports the fastest HPE ProLiant DDR4 memory (2933/3200 MT/s)
Typical HPE ProLiant DDR4 Memory Market Prices
Price ranges in the EU refurbished market:
Module | Typical Price (EUR) |
16GB RDIMM | 25–40 EUR |
32GB RDIMM | 40–70 EUR |
64GB LRDIMM | 70–140 EUR |
128GB LRDIMM | 180–350 EUR |
Prices depend on part number, rank, and current supply levels.
Why Enterprises Buy Refurbished HPE ProLiant DDR4 Memory
Most companies running HPE ProLiant Gen9/Gen10 servers choose refurbished memory because:
Lower cost
Long warranty from suppliers
Fully tested modules
Fast availability
Zero performance difference compared to new
Ideal for cost-controlled environments
This makes refurbished HPE ProLiant DDR4 memory one of the best ROI upgrades for existing infrastructure.
Choosing the Right HPE ProLiant DDR4 Memory Module
Step 1 – Identify your server model
HPE ProLiant DL380 Gen9, DL360 Gen10, ML350 Gen10, etc.
Step 2 – Check whether your server uses RDIMM or LRDIMM
Cannot mix.
Step 3 – Confirm the DDR4 speed based on CPU
2400, 2666, 2933, or 3200.
Step 4 – Select the capacity
16GB / 32GB → general workloads64GB / 128GB → virtualization, SAP, VDI, databases
HPE ProLiant DDR4 Memory Modules: Save Up To 80%
✔️ 5-Year Warranty – No Risk: Pay Only After Testing
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