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Best NVIDIA GPUs for HPE ProLiant Servers

  • Writer: server-parts.eu server-parts.eu
    server-parts.eu server-parts.eu
  • Mar 29
  • 4 min read

Updated: Oct 2

HPE ProLiant servers are widely used in enterprise environments, and many organizations are looking to add compatible NVIDIA GPUs to improve performance. Whether you're considering purchasing a complete HPE ProLiant server with NVIDIA GPUs or upgrading your existing setup, knowing which GPUs are compatible can be challenging.


NVIDIA GPUs for HPE Servers: Save Up To 80%

✔️ 5-Year Warranty – No Risk: Pay Only After Testing


In this article, we'll guide you through the best NVIDIA GPU options for your HPE ProLiant servers.


HPE ProLiant DL360 DL380 DL580 Gen10 Gen11 servers with NVIDIA GPUs including A10, A16, A30, A40, A100, H100, L40, RTX 6000 Ada for AI, HPC, VDI, virtualization, inference, machine learning, deep learning, data center workloads. server-parts.eu. refurbished. used.


HPE ProLiant DL360 GPU Server Series


HPE ProLiant DL360 Gen10 GPU Servers


Key Features:

✅ Supports 1 low-profile GPU

✅ Best for VDI environments and lightweight inference workloads


Supported GPUs:

  • NVIDIA A16 64GB – High-density VDI

  • NVIDIA T4 16GB – Low-power inference (PCIe Gen3)

  • NVIDIA P4 8GB – Ultra-low power inference (legacy)


Important Considerations:

  • Requires a GPU enablement kit

  • High-performance fans necessary for cooling in 1U



HPE ProLiant DL360 Gen10+ GPU Servers


Key Features:

✅ Supports 2 low-profile GPUs

✅ PCIe Gen4 for better bandwidth

✅ Great for VDI, inference, and light AI tasks


Supported GPUs:

  • NVIDIA A2 16GB – Efficient AI inference

  • NVIDIA A16 64GB – High-density VDI

  • NVIDIA T4 16GB – Low-power inference (PCIe Gen3)


Important Considerations:

  • GPUs over 75W require:

    • Power cable kit

    • Upgraded fans



HPE ProLiant DL360 Gen11 GPU Servers


Key Features:

✅ Supports 2 low-profile GPUs

✅ PCIe Gen5 for higher bandwidth

✅ Ideal for inference, VDI, and creative workloads


Supported GPUs:

  • NVIDIA L4 24GB – AI inference & video analytics

  • NVIDIA RTX 4000 Ada – Creative workstation graphics

  • NVIDIA A16 64GB – High-density VDI


Important Considerations:

  • Enhanced cooling and power cables required for GPUs >75W



HPE ProLiant DL380 GPU Server Series


HPE ProLiant DL380 Gen10 GPU Servers


Key Features:

✅ Supports up to 2 full-height GPUs

✅ Suitable for inference, visualization, and VDI


Supported GPUs:

  • NVIDIA A10 24GB – Virtual workstations & AI

  • NVIDIA A30 24GB – AI inference & training

  • NVIDIA A40 48GB – Rendering & visualization

  • NVIDIA A16 64GB – High-density VDI

  • NVIDIA T4 16GB – Low-power inference

  • NVIDIA V100 32GB – HPC & AI (Gen3)


Limitations:

  • A100 not supported (Gen3 bus limit)


Important Considerations:

  • GPUs >150W require:

    • Power cables

    • GPU enablement kit



HPE ProLiant DL380 Gen10+ GPU Servers


Key Features:

✅ Supports up to 3 full-height GPUs

✅ Strong for AI training, graphics, VDI


Supported GPUs:

  • NVIDIA A2 16GB – Efficient AI inference

  • NVIDIA A10 24GB – Virtual workstations & AI

  • NVIDIA A30 24GB – AI inference & training

  • NVIDIA A40 48GB – Rendering & visualization

  • NVIDIA A100 80GB – AI training & HPC


Important Considerations:

  • GPUs >300W require:

    • Enablement kit

    • Enhanced cooling



HPE ProLiant DL380 Gen11 GPU Servers


Key Features:

✅ Supports up to 4 full-height GPUs

✅ Optimized for AI, HPC, data-heavy workloads


Supported GPUs:

  • NVIDIA A10 24GB – Virtual workstations & AI

  • NVIDIA A16 64GB – High-density VDI

  • NVIDIA A30 24GB – AI inference & training

  • NVIDIA A40 48GB – Rendering & visualization

  • NVIDIA A100 80GB – AI training & HPC

  • NVIDIA H100 80GB – Advanced AI training

  • NVIDIA L40 48GB – Rendering & visual computing

  • NVIDIA L40S 48GB – Generative AI & inference

  • NVIDIA A6000 48GB – Creative & HPC workloads

  • NVIDIA RTX 6000 Ada – Professional visualization

  • NVIDIA RTX 5000 Ada – Mid-range AI & graphics


Important Considerations:

  • Multi-GPU configs require:

    • Upgraded PSUs

    • Enhanced cooling



HPE ProLiant DL560 GPU Server Series


HPE ProLiant DL560 Gen10 GPU Servers


Key Features:

✅ Supports 2 GPUs (PCIe Gen3)

✅ HPC, inference, legacy AI


Supported GPUs:

  • NVIDIA T4 16GB – Low-power inference

  • NVIDIA V100 32GB – HPC & AI (Gen3)


Important Considerations:

  • Enablement kit required

  • Cooling & power cabling for >150W

  • Compatibility depends on BIOS/system config



HPE ProLiant DL560 Gen11 GPU Servers


Key Features:

✅ Supports up to 2 GPUs

✅ Designed for AI, HPC, scientific computing


Supported GPUs:

  • NVIDIA H100 80GB – Advanced AI training

  • NVIDIA A40 48GB – Rendering & visualization

  • NVIDIA L40 48GB – Rendering & AI

  • NVIDIA L40S 48GB – Generative AI & inference

  • NVIDIA A800 80GB – Export-friendly AI training

  • NVIDIA H800 80GB – Export variant AI workloads


Important Considerations:

  • Enablement kit and strong power delivery required



HPE ProLiant DL580 GPU Server Series


HPE ProLiant DL580 Gen10 GPU Servers


Key Features:

✅ Supports multiple high-performance GPUs

✅ AI training, HPC, visualization


Supported GPUs:

  • NVIDIA A40 48GB – Rendering & visualization

  • NVIDIA A100 80GB – AI training & HPC

  • NVIDIA V100 32GB – HPC & AI (Gen3)


Important Considerations:

  • Dual 1600W PSUs recommended



HPE ProLiant DL580 Gen11 GPU Servers


Key Features:

✅ Supports multiple high-performance GPUs

✅ Designed for AI, graphics, data-heavy workloads


Supported GPUs:

  • NVIDIA L40 48GB – Rendering & graphics

  • NVIDIA L40S 48GB – Generative AI & inference

  • NVIDIA A40 48GB – Rendering & visualization

  • NVIDIA H100 80GB – AI training & HPC

  • NVIDIA A6000 48GB – Creative & HPC workloads

  • NVIDIA RTX 6000 Ada – Professional visualization

  • NVIDIA RTX 5000 Ada – Mid-range AI & graphics


Important Considerations:

  • Multi-GPU configs require:

    • High-wattage PSUs

    • Advanced cooling



NVIDIA GPUs for HPE Servers: Save Up To 80%

✔️ 5-Year Warranty – No Risk: Pay Only After Testing



Sources - NVIDIA GPUs for HPE ProLiant Servers


🔗 HPE Official Documentation

🔗 Community & Forum Discussions

🔗 Vendor / Partner Info


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